De novo NAD+ synthesis is ineffective for NAD+ supply in axenically cultured Caenorhabditis elegans
Abstract nacrack.com To secure an adequate nicotinamide adenine dinucleotide (NAD+) supply for survival, organisms typically rely on two complementary mechanisms: the de novo synthesis pathway and the salvage pathway.Notably, the classic quinolinic acid phosphoribosyltransferase (QPRTase) for de novo NAD+ synthesis is absent in Caenorhabditis elega